肝油不鹸化物 (殊にビタミンA) の燐酸エステルに関する研究 (第4報)

ビタミンAの尿中排泄に就て

抄録

Burden assays were carried out on the sodium and calcium salts of vitamin A phosphate and it was found that these were excreted into urine during saturation of vitamin A, 1 hour after subcutaneous injection of the sodium salt and within 3 hours of the oral administration of the calcium salt. The substance excreted was confirmed to be the partially oxidized substance of the phosphate. However, further examination would be necessary to determine whether all the vitamin A compounds are excreted into urine in a similar form. Comparative examination with other vitamin A preparations showed that the phosphate form gives a more rapid and reliable effects and would be valuable for the diagnosis of vitamine A deficiency.