Abstract
Manner of the formation of molecular compounds between p-aminomethylbenzene-sulfonamide (Homosulfamine) and sulfa drugs, and between sulfa drugs was examined by thermal analysis. The formation of molecular compounds was detected between Homosulfamine and sulfacetamide, sulfathiazole, phthalylsulfathiazole, sulfadiazine, Irgafen, and sulfisoxazole, and between diaminodiphenyl sulfone and sulfanilylthiourea. The molecular compounds are obtained as crystals from suitable solvents and their solubilities were found to be much greater than those of original sulfa drugs.
