γ, δ-不飽和β-ケト酸エステルのMichael縮合 (第1報)

Diethyl CrotonoylmalonateのMichael型自己縮合 その1

抄録

When diethyl crotonoylmalonate is treated under conditions for the Michael condensation, (1) diethyl β-methyl-γ-ethoxycarbonylglutarate is formed in the case of sodium ethoxide in ethanol, and dimethyl β-methyl-γ-methoxycarbonylglutarate with sodium methoxide in a large amount of methanol, (2) in the case of tert-butoxide in tert-butanol alcoholysis does not occur and there is no formation of the foregoing glutarate, and (3) in the case of piperidine, β-(1-piperidyl) butyrate is formed.