Diphenyl Etherを基核とするAcid Hydrazide誘導体の合成研究 (第4報)

Diphenyl Ether誘導体のHydrazide Hydrateに依る開裂反応 その2

抄録

Occurrence of hydrazinolysis in 4-nitrodiphenyl ether derivatives was found to be in following cases. When the substituent present in the benzene ring not possessing the nitro group is an ester of a carboxylic acid, and is in the ortho-position to the oxygen bond constituting the diphenyl ether linkage, then the cleavage occurs at ordinary pressure, and when at meta- or para-position, the reaction occurs only when carried out under a high pressure. When the said substituent is a free carboxylic acid, the cleavage occurs only under a high pressure, whether the group is in ortho-, meta-, or para-position. When the substituent is a methyl, the cleavage does not occur, either under ordinary or high pressure. 4-Nitrodiphenyl ether itself yields the corresponding 4-aminodiphenyl ether by the high pressure reaction.