3,4-ジメチルアニリン及び関連化合物の合成

抄録

1) Starting with 3, 4-dimethylbenzoic acid, pure 3, 4-dimethylaniline, free from other isomers, was obtained in 70-79% yield by the Schmidt reaction and in 40-43% yield by the Snyder reaction.
2) 3, 4-Dimethyl-1-ethoxycarbonylaminobenzene was obtained in a good yield by the Curtius reaction of 3, 4-dimethylbenzoic acid. Karrer and others described this substance as an oil but this was obtained as colorless prismatic crystals of m.p. 54-55°.
3) Nitration of 3, 4-dimethylaniline with a mixture of copper nitrate and acetic anhydrided afforded 6-nitro compound in a good yield.
4) 5, 6-Dimethyl-2-mercaptobenzimidazole and 5, 6-dimethylbenzimidazolyl-2-mercaptoacetic acid were also synthesized.