Reaction of 1 mole each of ethyl DL-dihydro-α-lipoate and acetic anhydride in pyridine at below 15° was found to result in a partial formation of ethyl DL-S6, S8-diacetyldihydro-α-lipoate, with the majority of ethyl DL-S8-acetyldihydro-α-lipoate. Ethyl DL-S6-acetyldihydro-α-lipoate was not obtained.
