YAKUGAKU ZASSHI
Online ISSN : 1347-5231
Print ISSN : 0031-6903
ISSN-L : 0031-6903
Studies on Optically Active Phenylpropanolamine Derivatives. VIII
The Preparation of Dimeric Ether of Phenylpropanolamines
Hideji Takamatsu
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1956 Volume 76 Issue 11 Pages 1241-1243

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Abstract
The reaction product obtained by l-ephedrine with perchloric acid or a small amount of conc. sulfuric acid was found to be d-bis (1-phenyl-2-methylaminopropyl) ether. Various kinds of dimeric ethers were prepared similarly from racemic and optically active ephedrine analogs. A small amount of phenylacetone was obtained as a by-product in this reaction.
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