Studies on the Syntheses of Hydrogenated Quinolines and Isoquinolines as Analgesics. V

Synthesis of 9-Phenethyl-N-methyl-1, 2, 3, 4, 6, 7, 8, 9-octahydroisoquinoline

Abstract

In an attempt to synthesize N-methyl-3-hydroxy-(4b, 8a-ethanoiminomethano)-4b, 5, 6, 7, 8, 8a, 9, 10-octahydrophenanthrene (B), its intermediate 9-phenethyl-N-methyl-1, 2, 3, 4, 6, 7, 8, 9-octahydroisoquinoline was prepared by the method shown graphically in the text, proving the feasibility of the synthesis of (B).