Studies on Submaxillary Gland. VIII

Studies on the Serum Ca Level Decreasing Principle in the Equine Submaxillary Gland

Abstract

The principle which effects decrease of serum calcium level in rabbits, contained in equine submaxillary gland, was found to be collected in a fraction of 12.5% sodium sulfate concentration from the pH 5.4-precipitate. This fraction, similar to parotin and S-parotin, were found to effect the circulating leucocyte counts in rabbits, the effect being the strongest among the various extracts of the equine submaxillary gland. Electrophoretic test of this fraction showed its purity to be 74.07% and the fraction was positive to general protein reaction. The maximum absorption in the ultraviolet spectrum appeared at 276mμ. This fraction was similar in many points to bovine S-parotin that it was designated as equine S-parotin.