YAKUGAKU ZASSHI
Online ISSN : 1347-5231
Print ISSN : 0031-6903
ISSN-L : 0031-6903
Studies on Synthetic Analgesics. X
Synthesis of Esters of α-(N-Methyl-piperazino) or Morpholino-Aliphatic Acids
Norio SugimotoNoboru ShigematsuSataro Imado
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1956 Volume 76 Issue 3 Pages 270-272

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Abstract
For the analgesic effect of analgesics, Prof. Ogyu forwarded a theory that there is a close relationship between the adrenergic and anticholinergic activities. Attempts were made to find two kinds of drugs each having such activities but not possessing any habituation tendencies in order to obtain a new analgesic without the fear of habituation. As a compound having such anticholinergic activity, fatty acid esters with N-methylpiperazino or morpholino groups in α-position were prepared.
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© by the PHARMACEUTICAL SOCIETY OF JAPAN
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