テラマイシン及び関連化合物の研究 (第8報)
Terracinoic Acidの合成
1956 年 76 巻 6 号 p. 739-742
詳細
1956 年 76 巻 6 号 p. 739-742
Terracinoic acid is an alkaline decomposition product of oxytetracycline and plays an important role in the structural determination of this antibiotic. The structure of terracinoic acid was proved to be 4-carboxy-5-hydroxy-3-methyl-indanone-2-acetic acid (XII) by its synthesis by the route shown and identification with terracinoic acid obtained by the direct degradation of oxytetracycline.
