抗生物質の理化学的研究 (第6報)

Streptomycilideneisonicotinylhydrazineの水溶液中における化学平衡について

抄録

In an aqueous solution, streptomycilideneisonicotinylhydrazine (Streptohydrazid) exists in an equilibrium of streptomycin and isonicotinic acid hydrazide (INAH). This equilibrium constant differs according to the pH of the solution, the value decreasing with increasing value of pH. This indicates that the equilibrium exists between streptomycin, INAH, and Streptohydrazid and that the difference in their concentration results in different dissociation of each compound and the original and product systems according to pH.