6-Ethoxyquinoline was derived to its 1-oxide (III) and the Reissert reaction of (III) and 6(or 7)-chloroquinoline 1-oxide afforded 6-ethoxy- (IV) and 6(or 7)-chloroquin-aldonitrile (I or II). The Reissert reaction of 6-ethoxy- and 7-chloro-quinoline afforded 1-benzoyl-6-ethoxy- (V) and 1-benzoyl-7-chloro-1, 2-dihydroquinaldonitrile (VI). The Reissert reaction of halogenated compounds or 3-bromo- and 4(5 or 8)-chloroquinolines results in dehalogenation and 1-benzoyl-1, 2-dihydroquinaldonitrile is formed.