YAKUGAKU ZASSHI
Online ISSN : 1347-5231
Print ISSN : 0031-6903
ISSN-L : 0031-6903
結核菌に対する化学療法剤の研究 (第15報)
2-Salicylidenehydrazono-4-thiazolidone関連化合物の合成及び抗菌作用 その8
谷山 兵三田中 幸夫内田 譽
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1957 年 77 巻 2 号 p. 210-211

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2-Salicylidenehydrazono-4-thiazolidone (I) derivatives with methyl, phenyl, and p-methoxyphenyl group in 3-position were prepared and their antituberculor action was tested. The compounds were prepared by deriving methylamine, aniline, and anisidine to 4-substituted thiosemicarbazides, condensed with salicylaldehyde, and further condensed with ethyl chloroacetate. These three kinds of 2-salicylidenehydrazono-3-alkyl (or aryl)-4-thiazolidones possessed much smaller antibacterial action than the original substance (I).
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© by the PHARMACEUTICAL SOCIETY OF JAPAN
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