1957 年 77 巻 5 号 p. 514-516
1) Reaction of hydroxylamine with quinazoline derivatives was further extended in order to examine its range of application and its reaction with 4-methylquinazoline afforded its 3-oxide as anticipated.
2) The structure of products obtained by these specific reaction of hydroxylamine was studied further and the present reaction product was identified as 4-methylquinazoline 3-oxide.
3) 4-Methylquinazoline 3-oxide can also be obtained by the reaction of 2-aminoacetophenone oxime and ethyl orthoformate.
4) An addition product was obtained from the reaction of 4-methylquinazoline and p-nitrobenzaldehyde and was assumed to be 4-(β-hydroxy-4-nitrophenethyl) quinazoline.