YAKUGAKU ZASSHI
Online ISSN : 1347-5231
Print ISSN : 0031-6903
ISSN-L : 0031-6903
6-Hydroxy-7-bromoquinolineの合成研究 (第2報)
5,7-Dibromo-6-hydroxyquinolineの5位の脱ブロム化反応について
藤田 栄一和気 典子
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1957 年 77 巻 7 号 p. 750-752

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Debromination of bromine in the 5-position of 5, 7-dibromo-6-hydroxyquinoline (III) with hydrobromic acid and phenol was examined and 6-hydroxy-7-bromoquinoline (II) was found to be obtained in a high yield when (III) is heated for 2 hours with 48% hydrobromic acid and phenol, with agitation. (II) is also obtained in a high yield when (III) is heated with phosphoric and sulfuric acids and glycerol.
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© by the PHARMACEUTICAL SOCIETY OF JAPAN
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