川骨成分の研究 (第12報)
Nupharamineについて
1957 年 77 巻 7 号 p. 792-793
詳細
1957 年 77 巻 7 号 p. 792-793
A new alkaloid, nupharamine, was obtained from nuphar, a dried rhizome of Nuphar japonicum DC. The alkaloid comes as a colorless, viscous liquid of b.p1 130-134°, [α]D8: -35.4°, C15H25O2N; forms a picrolonate of m.p. 167.5-168°, diacetyl compound of b.p0⋅25 166-169°, and N-methylnupharamine methiodide, m.p. 203.5°, on warming with methyl iodide. From its infrared spectrum, the presence of a furan ring was presumed. This base is a secondary amine and possesses one hydroxyl and one bridged oxygen that forms the furan ring. Presence of two C-methyl groups was predicted in nupharamine.
