抗糸状菌剤の研究 (第1報)
ウンデシレン酸水銀化合物の構造について
1957 年 77 巻 9 号 p. 1036-1037
詳細
1957 年 77 巻 9 号 p. 1036-1037
Reaction of mercuric acetate and sodium undecylenate in aqueous solution results in immediate precipitation of a mercury compound (II). In order to determine the structure of this compound, it was treated with potassium bromide and bromine to substitute the mercury with bromine and oxobromoundecanoic acid (VI) was obtained. Its debromination with sodium amalgam in ethanol or catalytic reduction with palladium black in methanol afforded 10-oxoundecanoic acid (VIII), m. p. 59°, whose semicarbazone (IX), m. p. 136°, agreed with data for this compound. It follows, therefore, that (VI) is 10-oxo-11-bromoundecanoic acid and the original mercury compound (II) would be 10-hydroxy-11-acetoxymercuriundecanoic acid.
