YAKUGAKU ZASSHI
Online ISSN : 1347-5231
Print ISSN : 0031-6903
ISSN-L : 0031-6903
ステロイドホルモンと血清蛋白の関係 (第2報)
ステロイドホルモンと牛血清アルブミン
滝川 泱男
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1958 年 78 巻 11 号 p. 1274-1279

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Fourteen kinds of steroidal hormone crystals were incubated with bovine serum albumin in a phosphate buffer of pH 8.0 at 36° and it was found that a part of the steroid became hydrophilic and lost solubility in organic solvents. The electrophoretic pattern of the bovine serum albumin incubated with steroids showed decreased height of the peak, thereby becoming asymmetric. In the serum albumin incubated with estrone, a small sub-peak appeared and δ-peak showed increased height. The amount of steroid in the buffer solution decreased with passage of time during incubation and reached a constant level after 24-48hours.

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© by the PHARMACEUTICAL SOCIETY OF JAPAN
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