Studies on the Constituents of Ericaceae. I

Isolation of Andromedotoxin (=Grayanotoxin I) from the Leaves of Rhododendron Metternichii var. typicum, Rh. japonicum, and Rh. Keiskei var. cardifolia

Abstract

A crystalline component, C₂₂H₃₆O₇, m. p. 259-260°, was isolated from Rhododendron Metternichii var. typicum, Rh. japonicum, and Rh. Keiskei var. cardifolia. This substance was found to be identical with grayanotoxin I, isolated from the leaves of Leucothoe Grayana by Miyajima and Takei, and with andromedotoxin, isolated from the leaves of Rh. maximum by Wood and others. The name of andromedotoxin (=grayanotoxin 1) was adopted.