3-Nitroquinoline 1-Oxideの接触還元について
1958 年 78 巻 6 号 p. 584-588
詳細
1958 年 78 巻 6 号 p. 584-588
Reduction of 3-nitroquinoline 1-oxide (I) was examined and it was found that reductive deoxygenation of the N-oxide group in the 3-nitro compound was much more facile than that in the 4-nitro compound. From the various data of reduction in solvents listed in Table I, it was found that this reduction was effected, as in the case of the 4-nitro compound, through 3-hydroxyamino- (II) and 3-amino-quinoline 1-oxide (III) to 3-aminoquinoline (IV). It was therefore considered that the facility of deoxygenation of the N-oxide group in 3-nitro and 4-nitro compounds could be explained as the difference in the electron density in the corresponding aminoquinoline 1-oxides.
