Studies on the Alkaloids of Menispermaceous Plants. CLXVIII

Alkaloids of Menispermum dauricum DC. (S uppl. 2). Synthesis of dl-Menisperine

Abstract

The racemic compound of menisperine (N-methylisocorydine) (X), the aporphinetype, phenolic quaternary base contained in Menispermum dauricum (Japanese name ‘Kohmori-kazura’) (Menispermaceae), was synthesized by the route shown in Chart 1. In this case, a by-product corresponding to benzylisoquinoline-type base, laudanine (VIII), was obtained during Pschorr's phenanthrene cyclization, besides the objective (X).