Abstract
Ethyl 9, 10-dimethoxy-1, 2, 3, 4, 6, 7-hexahydro-11bH-benzo [a] quinolizine-3-acetate (I) was submitted to reduction with lithium aluminum hydride and the alcohol compound (III) so obtained was derived to the bromide (III). Heating of this bromide in benzene produced intramolecular ammonium salt and 1-aza-bicyclo [3.3.1]-type compound (IV) was obtained in high yield. Similar reaction, starting with quinoline ester (V) afforded 1-azabicyclo[2.2.2]-type compound (IX).
