抄録
About 60 kinds of the compound of sulfonylurea series whose synthesis has been reported were examined for hypoglycemic action, using albino rats and several of these compounds were found to be comparable to D-860. One of these, 1-p-toluenesulfonyl-2-allylurea, was found to have a fairly strong action. A certain amount of conclusion was drawn regarding relationship between chemical structure and hypoglycemic action of these compounds. Sulfonylthiourea derivatives were almost devoid of hypoglycemic action but they are now being examined for other pharmacological activities.
