Zygadenine, the original alkamine of the hypotensive principle of domestic Veratrum plants, was derived to its acetonide and esters of zygadenine at 3-position, such as veratroylzygadenine, were prepared. Esters at 16- and 15, 16-positions were prepared by the use of these esters of zygadenine at 3-position.
