Decahydroisoquinoline誘導体の合成研究 (第7報)
2-Methyl-4-anisoyl-10-hydroxy-decahydroisoquinolineおよびその異性体の構造研究 その3 立体構造について
1960 年 80 巻 2 号 p. 145-152
詳細
1960 年 80 巻 2 号 p. 145-152
Comparative examinations were made on ultraviolet absorption spectra and pKa values between 2-methyl-4-anisoyl-10-hydroxydecahydroisoquinoline (IVα) and its isomer (IVβ), and sterecchemical considerations were made on their structure with the previously reported experimental results on their isomerization, dehydration, dehydration reaction of their Grignard-reaction products. It was finally concluded that it would be the most appropriate to assign dl-2-methyl-4α (or β)-anisoyl-10β (or α)-hydroxy-trans-decahydroisoquinoline for (IVα) and dl-2-methyl-4β (or α)-anisoyl-10β(or α)-hydroxy-trans-decahydroisoquinoline for (IVβ).
