Abstract
Novel acetylenic alcohols were prepared by the Grignard reaction or with sodium amide in liquid ammonia. 1-Phenylhex-4-en-1-yn-3-ol and 1, 5-diphenylpent-4-en-1-yn-3-ol were prepared as the en-yne alcohols, 1-(2-thienyl)-but-2-yn-1-ol and 1-(2-furyl)-but-2-yn-1-ol as heterocyclic acetylenic alcohols, and 1-phenylhepta-2, 4-diyn-1-ol, 1-(4-chlorophenyl)-hexa-2, 4-diyn-1-ol, 1-(2-hydroxyphenyl)-hexa-2, 4-diyn-1-ol, 1-(3-methoxy-4-hydroxyphenyl)-hexa-2, 4-diyn-1-ol, and 1-(1-naphthyl)-hexa-2, 4-diyn-1-ol as the diyne alcohols. Symmetric diyne alcohols, 1-di-(1-naphthyl)-hexa-2, 4-diyne-1, 6-diol and 1, 6-diphenylhexa-2, 4-diyne-1, 6-diol, were obtained in two isomers each, in pure state.
