YAKUGAKU ZASSHI
Online ISSN : 1347-5231
Print ISSN : 0031-6903
ISSN-L : 0031-6903
Studies on the Experimental Chemotherapy for Dermatomycosis and Candidiasis. I
On the Antifungal Activity of various Azophenol Compounds in vitro
Hiroshi Yamazoe
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1960 Volume 80 Issue 4 Pages 468-474

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Abstract
In vitro growth-inhibitory effect was examined with 56 kinds of azophenol series compounds, having 4-phenylazophenol as the fundamental skeleton and halogen or various other substituents introduced into its benzene ring, and three kinds of other azo compounds, using trichomycin, 10-hydroxy-11-hydroxymercuriundecanoic acid, and phenol as the controls, with Trichophyton asteroides, T. interdigitale, T. schoen-leinii, Microsporum gypseum, Epidermophyton floccosum, and Candida albicans as the test fungi. It was found that 4-(4-nitrophenylazo)-2-chlorophenol was able to inhibit the growth of test fungi in high dilutions of 1:1, 280, 000 to 1:2, 560, 000.
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