抄録
The venom of “Mamushi” (Agkistrodon halys blomhoffi BOIE) was submitted to chromatography over diethylaminoethylcellulose and substances with phosphodiesterase activity were obtained as two large peaks. These were designated diesterase-I and -II. The diesterase-I was further submitted to chromatography over carboxymethylcellulose and a peak with phosphodiesterase activity was found besides the large peak. This was found to be different from either diesterase-I or -II and was named diesterase-III. The diesterases-I, -II, and -III hydrolyzed RNA and DNA besides calcium bis [bis(p-nitrophenyl)phosphate] and the ratio of activities to these three substrates were different between diesterase-I and -II, or -III.
