アキカラマツThalictrum Thunbergii DC. のアルカロイド研究 (第8報)
ThalicberineおよびO-Methylthalicberineの構造 その4
1960 年 80 巻 8 号 p. 1137-1138
詳細
1960 年 80 巻 8 号 p. 1137-1138
Primary cleavage of thalicberine (I) itself with metallic sodium in liquid ammonia was carried out and the cleaved phenolic product thereby obtained was submitted to counter-current fractional extraction with a buffer solution of pH 5.6 to separate the unreacted material. The cleaved phenolic base (III) was methylated and the infrared absorption spectrum (in chloroform) of the O-methyl compound (+, +) (IV) so obtained was compared with that of the O-methyl ether of dauricine (V), i.e. O-methyldauricine (IV) (-, -), and the two spectra were found to be entirely identical. Consequently, (III) and (IV) were found to be optical antipodes.
