Antitumor Effect of Amino Acid Analogs

Abstract

Several series of compounds were found to have strong activity by the in vitro screening of 1, 300 organic compounds against tumor cell by the cell-agar plate method. Among these series of compounds, amino acid analogs and their related acylamino compounds were tested for the antitumor activity by the solid type Ehrlich ascites carcinoma in mice. Some methionine analogs showed marked effect against the tumor cells.