Abstract
It has been reported*1 that the Chinese drug _??__??__??_ (Shan-dou-gen), the radix of Sophora subprostrata, had anti-tumor activity and examinations were made on its components in order to elucidate its pharmaceutical effect. Presence of matrine, oxymatrine, anagyrine, methylcytisine, β-sitosterol, and lupeol was confirmed and two other substances were isolated; one of m. p. 145° (decomp.) and the other of m. p. 158°. The components of this radix were compared by paper partition chromatography with those of Euchresta japonica, Sophora flavescens, and Sophora japonica and a markedly fluorescent spot (spot K), considered to be due to the characteristic component of this radix, was detected.
