抄録
Methyl 8-formyl-6-oxoöxyoctanoate (III), obtained by application of formic acid to methyl 8-chloro-6-oxoöctanoate (I) or methyl 6-oxo-7-octenoate (II), was submitted to high-pressure reduction, followed by bromination and esterification, to form ethyl 6, 8-dibromoöctanoate (VI). α-Lipoic acid (XI) was prepared by the reaction of alkyl 6, 8-dihaloöctanoate (VI and VII) with sodium trithiocarbonate (VIII).
