YAKUGAKU ZASSHI
Online ISSN : 1347-5231
Print ISSN : 0031-6903
ISSN-L : 0031-6903
Studies on Synthetic Analgesics. XIII
Synthesis of Ethyl 2-Aminomethyl-3, 3-di(2-thienyl)acrylates
Noboru ShigematsuGoro Hayashi
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1961 Volume 81 Issue 3 Pages 421-423

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Abstract
A series of ethyl 2-aminomethyl-3, 3-di(2-thienyl)acrylates were prepared. These compounds were planned to agree with general rule for analgesics and to possess combined characteristics of dithienylaminobutene compounds and pethidine hydrochloride. However, their analgesic and antitussive actions were not as strong as were expected but were stronger than that of ethyl 2-aminomethyl-3, 3-diphenylacrylates.
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© by the PHARMACEUTICAL SOCIETY OF JAPAN
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