Abstract
Permanganate oxidation of aristolone and deoxoaristolone, obtained by its Wolff-Kishner reduction, gave aristoic acid, C15H20O5. Treatment of aristoic acid with mineral acid afforded a kind of phenolic carboxylic acid, C11H14O3, which was assumed to be a m-hydroxybenzoic acid derivative possessing methyl and isopropyl groups, by the determination of C-methyl group and absorption spectra. Based on this assumption, 3-isopropyl-5-hydroxy-o-toluic. acid was synthesized from 2-isopropyl-4-nitrotoluene and identity of the foregoing phenolic carboxylic acid was established.
