4-Iodopyridineおよびその同族体の合成
1961 年 81 巻 8 号 p. 1206-1207
詳細
1961 年 81 巻 8 号 p. 1206-1207
Diazotization of 4-amino-alkylpyridine 1-oxide by application of sodium nitrite at a low temperature and treatment with potassium iodide afforded 4-iodo-alkylpyridine 1-oxide in 40-70% yield. A solution of these 1-oxides dissolved in chloroform, added with phosphoryl chloride under ice cooling, and allowed to stand at room temperature or warmed on a water bath afforded 4-iodo-alkylpyridine in 60-90% yield.
