局所麻酔剤の研究 (第2報)
パラアミノ安息香酸誘導体の合成
1962 年 82 巻 6 号 p. 783-787
詳細
1962 年 82 巻 6 号 p. 783-787
Ethyl p-(2-dialkylaminoacylamino)benzoate and α-(2-dialkylaminoacylamino)benzamide derivatives were systematically prepared and examinations were made on the relationship between their chemical structure and local anesthetic activity. Of the 24 kinds of these compounds, the ester derivatives (XIV to XX) had almost equal to or better local anesthetic activity than procaine, with less toxicity.
