二, 三のベンゾチアジアジン誘導体の合成

3-置換-7-クロル-2H-1,2,4-ベンゾチアジアジン1,1-ジオキサイドおよび7-クロル-3-置換-3,4-ジヒドロ-1,2,4-ベンゾチアジアジン1,1-ジオキサイド

抄録

7-Chloro-3-methyl-1, 2, 4-benzothiadiazine-1, 1-dioxide which was reported by Rubin et al. as a substance having low blood pressure effect, without having saluric effect among benzothiadiazine derivatives was synthesized through the other route.
7-Chloro-3-substituted-3, 4-dihydro-2, 4-benzothiadiazine-1, 1-dioxide (3-methyl and 3-benzyl) were newly synthesized.