Abstract
In connection with the previous report that psoromic acid, one of depsidone series compounds of lichen substances, has antitumor action against Ehrlich ascites tumor, several kinds of depsidone of comparatively simple structure were synthesized in order to progress this work to a more complicated compounds of depsidone series. The compounds synthesized were as follows: 11-Oxo-11H-dibenzo[1, 4-b, e]dioxepin-8-car-boxaldehyde, 11-oxo-11H-dibenzo[1, 4-b, e]dioxepin-7-carboxaldehyde, 6-hydroxy-, 6-methyl-, 7-methyl-, and 8-methyl-11H-dibenzo[1, 4-b, e]dioxepin-11-one, and dibromo- and dibromo-8-propyl-11H-dibenzo[1, 4-b, e]dioxepin-11-one.
