YAKUGAKU ZASSHI
Online ISSN : 1347-5231
Print ISSN : 0031-6903
ISSN-L : 0031-6903
Reduction of Substituted Pyridinium Salts with NaBH4. (Supplement)
Oxidation of 1-Methyl-3-methoxycarbonyldihydropyridine with KMnO4
Nadao KinoshitaKazuko Oyama
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1963 Volume 83 Issue 2 Pages 207-209

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Abstract
It was found that 1-methyl-3-methoxycarbonyl-1, 6-dihydropyridine was oxidized by KMnO4 into 1-methyl-5-methoxycarbonyl-2(1H)-pyridone in cold acetone in comparatively better yield.
Following to this method, 2(1H)-pyridone compound was prepared from the corresponding 1, 4-dihydro compound but any pyridone compound 1-methyl-3-methoxy-carbonyl-1, 2, 5, 6-tetrahydropyridine did not undergo the oxidation in this condition.
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