YAKUGAKU ZASSHI
Online ISSN : 1347-5231
Print ISSN : 0031-6903
ISSN-L : 0031-6903
Studies on Tertiary Amine Oxides. XIX
Reactions of 4-Nitroquinaldine 1-Oxide with Acetyl Chloride
Masatomo HamanaSeitaro SaekiYayoi HatanoMasahiko Nagakura
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1963 Volume 83 Issue 4 Pages 348-351

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Abstract
Application of acetyl chloride to 4-nitroquinaldine 1-oxide results in consecutive formation of 4-nitroquinaldine 1-oxide (II), 4-chloroquinaldaldehyde 1-oxide oxime acetate (III) and or 4-chloroquinaldaldehyde 1-oxide (IV), and 4-chloroquinaldonitrile 1-oxide (V). Reaction of quinaldine 1-oxide, acetyl chloride, and silver nitrite takes exactly the same course. Structure of the products obtained by this reaction was clarified.
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© by the PHARMACEUTICAL SOCIETY OF JAPAN
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