Thioxolone誘導体のポーラログラフィー (第2報)
製剤中のThioxoloneの定量
1964 年 84 巻 11 号 p. 1138-1140
詳細
1964 年 84 巻 11 号 p. 1138-1140
Thioxolone (I) in each drug preparation was determined quantitatively by polarography. I is decomposed easily into 2, 2′-dithiodiresorcinol (II) in alkaline solution, which showed clear reduction wave on polarogram. I was determined quantitatively, according to the standard addition method by measuring II, produced from the alkali decomposition of I, which was extracted with ethanol from the preparations.
No effect was observed by the presence of phenol, resorcinol and bithionol in as much as five times quantity of I, however, a presence of hexachlorophen produced an effect remarkably.
