YAKUGAKU ZASSHI
Online ISSN : 1347-5231
Print ISSN : 0031-6903
ISSN-L : 0031-6903
Quinoline N-OxideとAlkylmagnesium Halideとの反応
加藤 鉄三山中 宏引地 学
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1965 年 85 巻 4 号 p. 331-334

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The reaction between quinoline N-oxide (I) and seven kinds of fatty Grignard reagents (R=methyl, ethyl, propyl, isopropyl, cyclohexyl, benzyl and phenethyl) has been studied and the production of 2-substituted quinoline N-oxide (II), 2-substituted quinoline (III) and quinoline (IV) have been observed. II and IV had never been produced in the Grignard reaction with I and the mechanism has been discussed.
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© by the PHARMACEUTICAL SOCIETY OF JAPAN
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