YAKUGAKU ZASSHI
Online ISSN : 1347-5231
Print ISSN : 0031-6903
ISSN-L : 0031-6903
サリバ・パロチン・Aによる白血球増加作用の検討
篠田 雅人高木 良成玉置 文一
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1966 年 86 巻 10 号 p. 906-910

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Action mechanism of the leukocytosis-promoting activity of Saliva Parotin-A was examined by using intact and X-irradiated rabbits. This activity of Saliva Parotin-A is chiefly carried on by granulocytes, and effects weak decreasing action on lymphocytes and monocytes. The serum from rabbits 2 and 6 hours after the administration of Saliva Parotin-A has a strong leukocytosis-promoting activity originating from granulocytes. Since the immunochemical measurement revealed that this reaction is not due to the originally administered Saliva Parotin-A, it is considered that a leukocytosis-promoting factor is produced secondarily in vivo by the administration of Saliva Parotin-A, and this factor appears in the serum. This factor was observed similarly in both X-irradiated and intact rabbits.

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© by the PHARMACEUTICAL SOCIETY OF JAPAN
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