Quantitative Analysis of Active Components in Ointments by X-Ray Diffractometry. II. : Analysis of Ammoniated Mercury (Hydrarg. Praec. Alb.) and Sulfur in Ointments.

Abstract

Quantitative determination was carried out on ointments (HPV and SV), which had white petrolatum (V) as the base and mercurous chloride (HP) or sulfurs as the chief constituent, as examples of an ointment using a chief constituent with greater coefficient of mass absorption, μ, than that of the ointment base. The determination was made by the X-ray diffraction method (direct method and the internal standard method using magnesium oxide as the standard). The direct method was found to give values with less reliability since the relationship between concentration and intensity of diffraction lines gave a bent curve, and the internal standard method seemed to be better in this case. The X-ray diffraction method, however, seemed to be practicable for determination.