1-Alkyl-2(1H)-pyridone誘導体の研究(第8報) : 1-Methyl-2(1H)-quinoloneと有機金属化合物の反応
1967 年 87 巻 5 号 p. 554-557
詳細
1967 年 87 巻 5 号 p. 554-557
Reaction between 1-methyl-2(1H)-quinolone (I) and phenyl-metal compound was carried out. Reaction conditions (reagent, solvent, and catalyst combination) and yields are given in Table I. The results of these reactions may be summarized into the following two points. (i) Reaction points of the phenyl-metal compound against I are considered to be at 2-, 4-, 5-, and 7-positions, but the reaction occurred only in the 2-position, in spite of various combinations of the reagent, solvent, and catalyst. The identified product was always only II. (ii) The yield of II was 48% at maximum but was calculated to be about 6O% when recovery of the starting material was taken into consideration.
