Isolation of (-)-trans-4-Hydroxypipecolic Acid from the Young Leaves of Acacia Mollissima

Abstract

It was found that (-)-trans-4-hydroxypipecolic acid (I) is present in young leaves of acacia species in a high concentration (as shown in Table I) and that the young leaves of Acacia mollissima before flowering time are useful as a natural source of I. The structure of I was determined by chemical reactions shown in Chart I.