Phenoxazine関連化合物の研究(第3報) : 1,2-Dihydroimidazo[4,5,1-kl]phenoxazine類の合成

抄録

Reaction of 2-tosyl-1, 2-dihydroimidazo [4, 5, 1-kl] phenoxazine (IV), which was prepared from 1-tosylaminophenoxazine (III) and methylene iodide, with lithium aluminum hydride gave 1, 2-dihydroimidazo [4, 5, 1-kl] phenoxazine (I). Detosylation of IV with 90% sulfuric acid, 25% hydrochloric acid, or by irradiation from a mercury lamp afforded imidazo [4, 5, 1-kl] phenoxazine (VI), accompanied with dehydrogenation. 1, 2-Dihydroimidazo [4, 5, 1-kl] phenoxazin-1-one (VIII) was synthesized from 1-aminophenoxazine (II) and phosgene. Reduction of tosyl (IX) or methyl compound (X) of VIII with lithium aluminum hydride afforded III or 1-dimethylaminophenoxazine (XI).