Isocarbostyril 関連化合物の合成研究(第1報) : 2-Methyl-3-aminoisocarbostyril と酸クロリドの反応
1971 年 91 巻 12 号 p. 1279-1285
詳細
1971 年 91 巻 12 号 p. 1279-1285
Reactions of 2-methyl-3-aminoisocarbostyril (I) with several acid anhydrides and acid chlorides were examined using acetic anhydride, acetyl chloride, benzoic anhydride, benzoyl chloride, oxalyl chloride and trans-cinnamoyl chloride. Acylation of C-4 in I, giving II, V, and X, took place predominantly in these cases, although the reaction of I with acryloyl chloride gave VIIa as the main product.
