中国産蛇床子およびハマゼリのクマリン成分について

抄録

Chinese crude drug "She Huangzi ( ?? ?? ?? ), " which has previously been presumed to be the fruits of a species of Cnidium from the morphological investigation, afforded eight known coumarins, columbianadin (I), archangelicin (II), edultin (III), O-acetylcolumbianetin (IV), bergapten (V), isopimpinellin (VI), columbianetin (VII), and O-isovalerylcolumbianetin (VIII), together with two new products which were proved to be 2'(S), 3'-(R)-3'-isobutyryloxy-O-acetyl-2', 3'-dihydrooroselol (IX) and 2'(S)-O-isobutyryl-2', 3'-dihydrooroselol (X). The herbs and roots of Cnidium japonicum M_IQ. contain I, IV, V, VI, VII, and X. These findings suggest that from the chemotaxonomical point of view, this crude drug can also be considered to be the fruits of Cnidium sp. The new product X was named cnidiadin.